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AGBT 2025 Review Part 1. Roche’s SBX Sequencing: The right enzymes power new sequencing chemistry

02/28/2025

At Active Site Partners, we were there at the beginning of Next Generation Sequencing. Over 20 years ago, Illumina (then Solexa) scientists introduced a groundbreaking sequencing method using reversible terminator chemistry and an innovative approach to amplifying DNA in clusters.…

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A picture of the chemical structure for lysine and lactylsinene.

Post-Translational Modification regulates DNA repair and suggests new therapeutic targets.

01/08/2024

A host of protein post-translational modifications (PTMs) have been discovered and play important roles in cellular regulation and metabolism. Recently, a new PTM was discovered that modifies protein lysine to lactyllysine in histones and plays an important role in regulation…

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